Pathological jaundice in neonates


The most common cause of hemolytic jaundice is ABO hemolysis, which is caused by incompatibility between the mother’s blood type and the fetus. Others such as maternal blood type A, fetal blood type B or AB; maternal blood type B, fetal blood type A or AB is less common, resulting in less jaundice. In this way, some parents will be very nervous, worried that the child will have ABO hemolysis, in fact, to explain: not all ABO system blood type is inconsistent, newborns will have hemolysis. According to reports, the incidence of ABO incompatible hemolysis in neonates was 11.9%. Neonatal hemolytic jaundice is characterized by the birth of jaundice within 24 hours and gradually worsens.

Infectious jaundice is a jaundice caused by a viral infection or a bacterial infection. Most of the viral infections are intrauterine infections. Cytomegalovirus and hepatitis B virus infections are the most common. Other infections include rubella virus, EB virus, Toxoplasma gondii, etc. Septic jaundice is the most common bacterial infection. Astragalus is characterized by persistent jaundice after discontinuous retraction of physiological jaundice or physiological jaundice.

Obstructive jaundice is caused by congenital biliary malformation. Congenital biliary wear is more common. The jaundice is characterized by recurrence of jaundice 1-2 weeks or 3-4 weeks after birth, gradually deepening, and the stool color becomes lighter and yellower. And even shows the white clay color.

Breast milk jaundice is a special type of pathological jaundice. A small number of breastfed newborns have a higher degree of jaundice than normal jaundice, and the reasons are not fully understood. The characteristics of jaundice are: After the peak of physiological jaundice, jaundice continues to increase, bilirubin can reach 10-30 mg / dl. If you continue to breastfeed, jaundice can slowly decline to a high level after a period of time. If you stop breastfeeding for 48 hours, The reduction in bilirubin is clearly 50%, and if breastfeeding again, bilirubin rises again.


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